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2023-2025年葡京娱乐场官网平台 代表性论文

序号论文题目发表时间期刊名称中科院分区影响因子
1Disease-state protein coronas reprogram 70-nm gold nanoparticle uptake via complement–apolipoprotein opsonization in glioblastoma cohorts2025-12-15Chemical Engineering Journal一区13.2
2GSH-Triggered Self-Cascading Nanoreactor Integrates Efficient ICD Induction and Immune Checkpoint Blockade for Pancreatic Cancer Therapy2025-11-17Advanced Functional Materials一区19
3Unraveling the therapeutic landscape of approved non-peptide macrocycles2025-07-10ACTA PHARMACEUTICA SINICA B一区14.6
4Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota2025-08-20Adv Sci (Weinh)一区14.1
5Zexie Tang Polysaccharides (ZXTPs) alleviate high-fat diet-inducedNAFL inmice through improving intestinal microbiota imbalance and liver metabolic dysfunction2025-06-30Carbohydrate Polymers一区12.5
6Sono-triggered nanoamplifier mediates ferroptosis-immune regulation  against bacterial pneumonia2025-11-10Journal of Controlled Release一区11.5
7Self-assembled triptolide prodrug nanovesicles loading with ginsenoside  Rg3 for double-targeted therapy of pancreatic cancer2025-06-17MATERIALS TODAY BIO一区10.2
8Preparation of zwitterionic covalent organic framework for high  throughout extraction of fluoroquinolones from lake water and milk2025-08-10Food Chemistry一区9.8
9Extraction of polysaccharides from Polygonum cuspidatum with activity against Type 2 Diabetes via alterations in gut microbiota2025-04-01Food Chemistry一区9.8
10Atractylenolide III alleviates cerebral ischemia-reperfusion injury by targeting Keap1 to activate the Nrf2/HO-1 pathway2025-10-10Phytomedicine一区8.3
11Multiscale insights into cornuside's effects on NAFLD: A cross-disciplinary integrating bioinformatics, computational chemistry, and machine learning2025-07-01Phytomedicine一区8.3
12Multi-omics analysis of the active components and mechanisms of Baojin Chenfei formula in silica-induced murine silicosis2025-06-17Phytomedicine一区8.3
13Exploring the anti-inflammatory effects of Radix Curcumae essential oil in pulmonary sarcoidosis via the TLR4/MyD88/NF-κB pathway2025-04-16Phytomedicine一区8.3
14The microglial state transition as a novel mechanism by which fresh Baihe Dihuang decoction prevents depression by regulating SIRT1/HMGB1 signaling2025-04-01Phytomedicine一区8.3
15Effective compound combination of Bufei Yishen formula ameliorates PM2.5-induced COPD by inhibiting mitochondrial oxidative stress through SIRT3-mediated FOXO3 deacetylation2025-03-13phytomedicine一区8.3
16Effective-compounds of Jinshui Huanxian Formula acts as an SRC inhibitor to inhibit HK2-mediated H3K18 lactation and improve pulmonary fibrosis2025-03-08Phytomedicine一区8.3
17Screening effective-component compatibility from Jinshui Chenfei formula for silicosis treatment by serum-pharmacochemistry and feedback system control2025-01-21Phytomedicine一区8.3
18Unlocking the Therapeutic Potential of Natural Products for Alzheimer's Disease2025-01-27JOURNAL OF MEDICINAL CHEMISTRY一区6.8
19Characterization of Lipid Epi-metabolites/reaction as Diagnostic Biomarkers for Idiopathic Pulmonary Fibrosis by Lipidepifind2025-10-17Analytical chemistry一区6.7
20Shenghui decoction inhibits neuronal cell apoptosis to improve Alzheimer's disease through the PDE4B/cAMP/CREB signaling pathway2025-01-01Phytomedicine一区6.7
21Discovery of Atractylenolide Derivatives as Novel LSD1 Inhibitors for the Treatment of  Alzheimer's Disease2025-06-05JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY一区6.2
22Photocatalyzed Oxycarboranylation and Hydrocarboranylation of Unsaturated C-C Bonds with 1-Iodo-2-methyl-o-carboranes as the Synthon2025-08-13organic letters一区5
23Photocatalzyed Oxycarboranylation of Alkenes with 1-Iodo-o-Carboranes through a Halogen-Atom Transfer Strategy2025-06-15Organic Letters一区5
24Lipolysis engages CD36 to promote ZBP1-mediated necroptosis-impairing lung regeneration in COPD2024-09-17Cell Reports Medicine一区11.7
25In situ injectable hydrogel encapsulating Mn/NO-based immune nano-activator for prevention of postoperative tumor recurrence2024-04-01Asian Journal of Pharmaceutical Sciences一区10.7
26Molecular mechanism of Chang Shen Hua volatile oil modulating brain cAMP-PKA-CREB pathway to improve depression-like behavior in rats2024-07-25phytomedicine一区10.6
27pH/GSH dual-responsive nanoparticle for auto-amplified tumor therapy of breast cancer2024-06-10Journal of Nanobiotechnology一区10.6
28Preparation and evaluation of a tryptophan based hypercrosslinked porous polymer as an efficient adsorbent for pipette tip solid-phase extraction of sulfonamides2024-01-26Food Chemistry一区8.5
29Oleanolic acid derivative self-assembled aggregates based on heparin and chitosan for breast cancer therapy2024-10-11INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES一区7.7
30Mechanistic insights into the treatment of pulmonary fibrosis with bioactive components from traditional chinese medicine via matrix stiffness-mediated EMT2024-11-17Phytomedicine一区6.7
31Recent advances in the therapeutic potential of nobiletin against respiratory diseases2024-06-03Phytomedicine一区6.7
32Alisol B regulates AMPK/mTOR/SREBPs via directly targeting VDAC1 to  alleviate hyperlipidemia2024-06-01Phytomedicine一区6.7
33Lentinan-functionalized PBAE-G-nanodiamonds as an adjuvant to induce cGAS-STING pathway-mediated macrophage activation and immune enhancement2024-12-01Journal of Pharmaceutical Analysis一区6.1
34Platforms of graphene/MXene heterostructure for electrochemical  monitoring of rutin in drug and Tartary buckwheat tea2024-01-01talanta一区6.1
35Astragaloside I Promotes Lipophagy and Mitochondrial Biogenesis to Improve Hyperlipidemia by Regulating Akt/mTOR/TFEB Pathway2024-10-01J Agric Food Chem一区5.7
36Selective extraction and analysis of phenolic acids in herbal plants using Fe3O4@MXene@PEI aerogel2024-08-25Talanta一区5.6
37Photoredox/copper catalyzed one-pot aminoalkylation/cyclization of alkenes with primary amines to synthesize polysubstituted γ-lactams2024-01-22Organic Letters一区4.9
38Inhibition of ferroptosis through regulating neuronal calcium homeostasis: An emerging therapeutic target for Alzheimer's disease2023-03-02Ageing Research Reviews一区13.1
39Hederagenin improves Alzheimer’s disease through PPAR α /TFEB-mediated autophagy2023-04-01Phytomedicine一区7.9
40Synthesis, characterization and anti-breast cancer activities of stachydrine derivatives2023-10-01European Journal of Medicinal Chemistry一区6.7
41Effective-compounds of Jinshui Huanxian formula ameliorates fibroblast activation in pulmonary fibrosis by inhibiting the activation of mTOR signaling2023-01-15PHYTOMEDICINE一区6.7
42Yishen Tongluo formula alleviates diabetic kidney disease through regulating Sirt6/TGF-β1/Smad2/3 pathway and promoting degradation of TGF-β12023-02-03Journal of Ethnopharmacology一区5.4
43Photoredox/copper-catalyzed formal cyclopropanation of olefins2023-12-23Organic Chemistry Frontiers一区4.6
44Preparation, identification, and application of PEG/ZIF-8@ Dendrobium huoshanense polysaccharide as an adjuvant to enhance immune responses2023-12-01Fish Shellfish Immunol一区4.1
45Dispersive solid-phase extraction of alkaloids and polyphenols using borate hypercrosslinked polymers2023-07-06Journal of Separation Science一区3.1
46Targeting aldose reductase in pulmonary fibrosis: Blocking de novo fatty  acid synthesis halts pro-fibrotic M2 polarization2025-12-09International Journal of Biological Macromolecules二区8.5
47A charge reversal nanomedicine based on dual pH-responsive crosslinked  dextran-based polysaccharide for synergistic cancer chemo/  chemodynamic therapy2025-09-30INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES二区8.5
48Ultrasound-assisted non-starch polysaccharide extraction from bulbils of Dioscorea opposita maxim and its bioactivity on ulcerative colitisvia improving the intestinal barrier and modifying the gut microbiota2025-08-05International Journal of Biological Macromolecules二区8.5
49RGD peptide/dextran sulfate-based nanocarriers loaded with triptolide for  double-targeted apoptosis of both tumor cells and M2-like TAMs in  pancreatic cancer therapy2025-05-06INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES二区8.5
50Synergistic effect of pH-sensitive PEGylated RG3-chitosan prodrug  nanoparticles encapsulated celastrol on pancreatic cancer2025-12-01Drug Delivery二区8.1
51Bioactive ligands targeting ectopic olfactory receptors: Implications for therapeutic strategies2025-08-05British Journal of Pharmacology二区7.7
52Gold/Prussian Blue-Based Nanocomposites with  Dual Nanozyme Activities Exert a Synergistic  Effect of Starvation Therapy and Sonodynamic  Therapy in the Treatment of Liver Cancer2025-09-01International Journal of Nanomedicine二区6.5
53Formononetin ameliorates depression-like  behaviors through rebalancing microglia  M1/M2 polarization and inhibiting NLRP3  inflammasome: involvement of activating  PPARα-mediated autophagy2025-04-24Molecular Medicine二区6.4
54Cycloastragenol Regulates Mitochondrial Homeostasis-Mediated Renal Tubular Injury to Ameliorate Diabetic Kidney Disease by Directly Targeting ERK to Modulate TFEB2025-12-04phytotherapy research二区6.3
55Pharmacological Regulation of Mitophagy by Natural Plant  Products as a Therapeutic Target for Alzheimer's Disease2025-10-08Phytotherapy Research二区6.3
56Atractylenolide ⅠⅠⅠ mitigates alzheimer’s disease by enhancing autophagy via the YY1-TFEB pathway2025-08-24phytotherapy research二区6.3
57Effects of Saffron Supplementation on Glycolipid Metabolism and Blood Pressure in Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials2025-05-14PHYTOTHERAPY RESEARCH二区6.3
58Berberine-based hypercrosslinked polymer: Advanced solid-phase  microextraction for high-throughput analysis of aristolochic acids in  environmental water and herbal plants2025-06-04Talanta二区6.1
59Isoliquiritigenin Exhibits Anti-Inflammatory Responses in Acute Lung Injury by Covalently Binding to the Myeloid Differentiation Protein-2 Domain2025-02-01Phytotherapy Research二区6.1
60Recent development in PDE4D-targeted inhibitors for Alzheimer’s  disease therapy2025-11-17European Journal of Medicinal Chemistry二区5.9
61Electroacupuncture stimulation improves pulmonary fibrosis by modulating ferroptosis in rats: multiscale analysis of transcriptome and proteome2025-08-20Chinese medicine二区5.7
62PEGylated retinoate prodrug self-assembled nanomicelles loaded with  triptolide for targeting treatment of rheumatoid arthritis and side  effect attenuation2025-03-04COLLOIDS AND SURFACES B-BIOINTERFACES二区5.6
63Total flavonoids of Prunella vulgaris exert anti-hepatocellular carcinoma effects through autophagy suppression mediated by activation of the PI3K/AKT/mTOR pathway2025-11-13J Ethnopharmacol二区5.4
64Multi-target neuroprotection of Atractylodes macrocephala ethyl acetate  extract against Alzheimer’s disease: from bioactivity-guided screening to  mechanistic validation2025-10-15Journal of Ethnopharmacology二区5.4
65Chaihu Longgu Muli Decoction attenuates chronic stress-induced  endothelial dysfunction and potentiates chemotherapy in breast cancer by  inhibiting cAMP/PKA/CREB1 mediated glycolysis2025-09-29Journal of Ethnopharmacology二区5.4
66Ferulic acid derived from Huanshaodan improves cognitive deficits in Alzheimer’s disease model through regulating APP proteolytic processing via downregulation of SIRT2 expression2025-08-29Journal of Ethnopharmacology二区5.4
67Integrating single-cell analysis and machine learning to identify COPD hub  genes and explore the intervention mechanism of effective component  compatibility of Bufei Yishen formula III2025-07-24Journal of Ethnopharmacology二区5.4
68Inhalation of Acori Tatarinowii Rhizoma essential oil alleviates dyskinesia in Parkinson's disease rats through the regulation of neuroinflammation2025-05-28JOURNAL OF ETHNOPHARMACOLOGY二区5.4
69Integrated multi-omics analysis and experimental validation reveals the  mechanism of tenuifoliside A activity in Alzheimer’s disease2025-04-08Journal of Ethnopharmacology二区5.4
70Fuzi Lizhong Pill inhibited inflammatory response and promoted colon mucosal healing in dextran sulfate sodium-induced ulcerative colitis mice by down-regulating PI3K/AKT/NF-κB signaling pathway2025-03-13Journal of Ethnopharmacology二区5.4
71P-coumaric-acid ameliorates acute kidney injury induced by ischemia-reperfusion injury via suppressing ferroptosis2025-11-08Journal of Nutritional Biochemistry二区4.9
72A New Perspective on Regenerative Medicine: Plant-Derived Extracellular Vesicles2025-06-28Biomolecules二区4.8
73Integrated miRNAome, transcriptome, and degradome analyses reveal the role of miRNA–mRNA modules in the biosynthesis of oridonin in Isodon rubescens2025-06-18Frontiers in Plant Science二区4.8
74Mechanism of Atractylodis Rhizoma in improving cognitive dysfunction in  Alzheimer’s disease by regulating the cAMP/CREB/BDNF pathway2025-11-19International Immunopharmacology二区4.7
75Baicalin and kaempferol alleviates cuprizone-induced demyelination and microglial activation by inhibiting the STAT3 and NF-κB signaling pathways2025-05-08International Immunopharmacology二区4.7
76Isolation and identification of sesquiterpenes from the aerial parts of Chloranthus japonicus and their chemosensitizing activities on U2 OS cells - 副本2025-01-18Journal of Molecular Structure二区4.7
77Synergistic therapy of Chinese herbal medicine and gut microbiota modulation for post-stroke cognitive recovery: focus on microbial metabolite and immunoinflammation2025-08-14Frontiers in Microbiology二区4.5
78Research Progress in the Molecular Mechanism of NLRP3  Inflammasome in Alzheimer’s Disease and Regulation by Natural Plant  Products2025-01-28Molecular Neurobiology二区4.3
79Metabolomic and microbial insights: Kai-Xin-San’s impact on Alzheimer’s disease pathology2025-07-18iScience二区4.1
80Sulfonic acid-functionalized covalent organic framework@Ti3C2Tx as  efficient solid-phase microextraction blade coating for the extraction of  monoamine neurotransmitters in rat serum samples2025-10-08Journal of Chromatography A二区4
81Tumor Microenvironment-Responsive Biodegradable Nanomedicine for Self-Enhanced Synergistic Chemo?, Photothermal, and Chemodynamic Therapy2024-09-20ACS APPLIED MATERIALS & INTERFACES二区8.5
82Oleanolic acid derivative self-assembled aggregates based on heparin and chitosan for breast cancer therapy2024-08-30Int J Biol Macromol二区8.5
83Artemisia argyi H. Lév. & Vaniot: a comprehensive review on traditional uses, phytochemistry, and pharmacological activities2024-01-24 Phytochemistry Reviews 二区7.3
84Disulfide bond-based oxidationresponsive triptolide-loaded nanodrug for inflammation-targeted treatment of collagen-induced arthritis2024-07-12APPLIED MATERIALS TODAY二区7.2
85Disulfide bond-driven redox-responsive triptolide-loaded nanodrug for inflammation-targeted treatment of collagen-induced arthritis2024-06-01Applied Materials Today二区6.9
86Chinese herbal medicine-derived extracellular vesicles as novel biotherapeutic tools: present and future2024-11-25Journal of Translational Medicine二区6.1
87The Mutual Regulatory Role of Ferroptosis and Immunotherapy in Anti-tumor Therapy2024-06-09Apoptosis  .二区6.1
88Efficacy and Mechanisms of Natural Products as Therapeutic Interventions for Chronic Respiratory Diseases2024-02-14The American Journal of Chinese Medicine二区5.7
89Polygonum cuspidatum polysaccharide: A review of its extraction and purification, structure analysis, and biological activity2024-09-15Journal of Ethnopharmacology二区5.4
90Mechanism underlying the therapeutic effects of effective component compatibility of Bufei Yishen formula III combined with exercise rehabilitation on chronic obstructive pulmonary disease.2024-12-01Annals of Medicine二区4.9
91Identification of idiopathic pulmonary fibrosis hub genes and exploration of the mechanisms of action of Jinshui Huanxian formula2024-05-27International Immunopharmacology二区4.9
92Magnolol preserves the integrity of the intestinal epithelial barrier and  mitigates intestinal injury through activation of PPAR γ in COPD rat2024-12-01Journal of Ethnopharmacology二区4.8
93Kaempferol improves depression-like behaviors through shifting microglia polarization and suppressing NLRP3 via tilting the balance of PPARγ and STAT1 signaling2024-11-03International Immunopharmacology二区4.8
94Nobiletin alleviates macrophage M2 polarization by activating AMPK-mTOR-mediated autophagy in pulmonary fibrosis mice2024-09-30International Immunopharmacology二区4.8
95Astragaloside I from Astragalus Attenuates Diabetic Kidney Disease by Regulating HDAC3/Klotho/TGF-β1 Loop2024-09-30American Journal of Chinese Medicine二区4.8
96Network pharmacology and experimental validation reveal the mechanisms of sniffing essential oil of Acori Tatarinowii rhizoma in treating olfactory dysfunction2024-09-24J Ethnopharmacol二区4.8
97Integration of network pharmacology and experimental verification to reveal the active components and molecular mechanism of modified Danzhi Xiaoyao San in the treatment of depression2024-08-23Journal of Ethnopharmacology二区4.8
98Effective-components combination alleviates PM2.5-induced inflammation by evoking macrophage autophagy in COPD2024-03-01Journal of Ethnopharmacol二区4.8
99Exploring the anti-ferroptosis mechanism of Kai-Xin-San against Alzheimer's  disease through integrating network pharmacology, bioinformatics, and experimental  validation strategy in vivo and in vitro2024-02-13Journal of ethnopharmacology二区4.8
100The traditional herb Sargentodoxa cuneata alleviates DSS-induced colitis by attenuating epithelial barrier damage via blocking necroptotic signaling2024-01-01Journal of Ethnopharmacol二区4.8
101Golm1 facilitates the CaO2-DOPC-DSPE200-PEI -CsPbBr3 QDs -induced apoptotic death of hepatocytes through the stimulation of mitochondrial autophagy and mitochondrial reactive oxygen species production through interactions with P53/Beclin-1/Bcl-22024-08-01Chem Biol Interact二区4.7
102Cryptotanshinone alleviates liver ffbrosis via inhibiting STAT3/  CPT1A-dependent fatty acid oxidation in hepatic stellate cells2024-06-25Chemico-Biological Interactions二区4.7
103Huanshaodan regulates microglial glucose metabolism reprogramming to alleviate neuroinflammation in AD mice through mTOR/HIF-1α signaling pathway2024-07-26Front. Pharmacol.二区4.4
104Deciphering the multi- partite mitochondrial  genome of Crataegus pinnatifda: insights  into the evolution and genetics of cultivated  Hawthorn2024-10-07BMC Plant Biology二区4.3
105Periostracum Cicadae Extract and N-Acetyldopamine Regulate the Sleep-Related Neurotransmitters in PCPA-Induced Insomnia Rats2024-07-04molecules二区4.2
106Natural Product-Derived Phytochemicals for Influenza A Virus (H1N1) Prevention and Treatment2024-05-17Molecules二区4.2
107Comparative Pharmacokinetics Research of 13 Bioactive  Components of Jieyu Pills in Control and Attention Deficit  Hyperactivity Disorder Model Rats Based on UPLC-Orbitrap  Fusion MS2024-03-10Molecules二区4.2
108Discovery of the Active Compounds of the Ethyl Acetate Extract Site of Ardisia japonica (Thunb.) Blume for the Treatment of Acute Lung Injury2024-02-07Molecules二区4.2
109Functional elucidation of the EIF4A3–circR-4225–miR-507–TNFSF11 regulatory axis in LUAD and its role in tumor progression2024-08-28Scientific Reports二区3.8
110A Dual-responsive RhB-doped MOF probe for Simultaneously Recognition of Cu2+ and Fe3+2024-05-23Scientific Reports二区3.8
111Efficacy and safety of Supine Daoyin in the treatment of acute exacerbation of chronic obstructive pulmonary disease: A randomized controlled trial2024-09-01Journal of Evidence Based Medicine二区3.6
112An ultra-high disulfiram-loaded delivery system achieved by supercritical carbon dioxide technology for copper-enhanced chemotherapy2023-02-01Journal of CO2 Utilization二区7.7
113Rational design of 4-((6-phenoxypyrimidin-4-yl) amino)-N-(4-(piperazin-1-yl)phenyl)-1H-pyrazole-3-carboxamide (LT-540-717) as orally bioavailable FLT3 inhibitor2023-08-01Eur J Med Chem二区6.7
114Design, synthesis and in vitro/in vivo anticancer activity of  tranylcypromine-based triazolopyrimidine analogs as novel LSD1 inhibitors2023-05-05EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY二区6
115Radix Rehmanniae Praeparata (Shu Dihuang) exerts neuroprotective effects on ICV-STZ-induced Alzheimer’s disease mice through modulation of INSR/IRS-1/AKT/ GSK-3β signaling pathway and intestinal microbiota2023-02-01Frontiers in Pharmacology二区5.988
116Red blood cell membrane-coated functionalized Au nanocage as a biomimetic platform for improved MicroRNA delivery in hepatocellular carcinoma2023-07-02International Journal of Pharmaceutics二区5.8
117Metabolomic profiling combined with network?analysis of serum pharmacochemistry to reveal the therapeutic mechanism of Ardisiae Japonicae Herba against acute lung injury2023-07-01Frontiers in Pharmacology二区5.6
118Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice2023-10-01J Ethnopharmacol.二区5.4
119Reduction of Th2 inflammation and fibrosis in eosinophilic esophagitis in a murine model by citri reticulatae pericarpium2023-08-01Journal of Ethnopharmacology二区5.4
120Clinical efficacy of weight loss herbal intervention therapy and lifestyle modifications on obesity and its association with distinct gut microbiome: A randomized double-blind phase 2 study2023-03-22Frontiers in Endocrinology二区5.2
121A Pharmacokinetic Study of Sixteen Major Bioactive Components of Jinshui-Huanxian Granules in Pulmonary Fibrosis Model and Control Rats Using Orbitrap Fusion Mass Spectrometry2023-09-01Molecules二区4.9
122Investigation of the interaction between the functionalized mesoporous silica nanocarriers and bovine serum albumin via multi-spectroscopy2023-05-01Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy二区4.4
123Efficacy and safety of Kangxian Huanji Granule as adjunctive treatment in acute exacerbation of idiopathic pulmonary fibrosis: An exploratory randomized controlled trial2023-11-01J Integr Med二区4.2
124Guidelines of integrated Chinese and western medicine for diagnosis and treatment of chronic obstructive pulmonary disease (2022)2023-12-01Journal of Evidence Based Medicine二区3.6
125Guideline on Establishing Diagnostic Criteria for Chinese Medicine Syndromes2023-12-01Journal of Evidence Based Medicine二区3.6